What antidote is used for dystonic reactions?

Dystonic reactions are acute, involuntary muscle contractions or spasms that often arise as side effects from antipsychotic medications, particularly those that are dopamine antagonists. In the treatment of these reactions, an anticholinergic medication is commonly employed to provide rapid relief of symptoms.

Benztropine is an anticholinergic drug that is effective in counteracting the musculoskeletal effects associated with dystonia. It works by inhibiting acetylcholine activity in the central nervous system, which helps to restore a balance affected by dopaminergic antagonism. By administering benztropine, healthcare providers can alleviate the discomfort and muscular dysfunction that patients experience during dystonic reactions.

Other options, such as psychotherapy, haloperidol, and fluoxetine, target different disorders or symptoms. Psychotherapy is not a pharmacological treatment for dystonia. Haloperidol, while it is an antipsychotic that can induce dystonic reactions, does not serve as an antidote for such events. Fluoxetine, an SSRI used primarily for depression and anxiety, has no utility in treating dystonia. Thus, benztropine remains the primary choice for managing dystonic reactions effectively.