Tenecteplase (TNKase) is administered in what manner?

Tenecteplase (TNKase) is a thrombolytic agent used primarily for the treatment of acute myocardial infarction. It is designed to quickly dissolve blood clots. The administration of Tenecteplase is specifically done as a single intravenous bolus, which is an important characteristic of this medication. The rapid administration over a short duration, specifically 5 seconds, enhances its efficacy in acute situations where quick intervention is crucial to restore blood flow.

This method of administration allows for immediate distribution into the bloodstream, making it advantageous in emergency medical scenarios, such as during a heart attack. In contrast, options like intravenous administration over an hour or continuous infusion are not applicable for Tenecteplase, as they would not provide the rapid action necessary to address the urgent nature of thrombotic events. Additionally, intramuscular injection is contra-indicated due to the risk of bleeding and complications associated with thrombolytic therapy.