Prinzide and Zestoretic are combinations of which two medications?

Prinzide and Zestoretic are combinations of lisinopril and hydrochlorothiazide (HCTZ). Lisinopril is an angiotensin-converting enzyme (ACE) inhibitor that works by relaxing blood vessels and lowering blood pressure, while HCTZ is a thiazide diuretic that helps to reduce blood pressure by eliminating excess fluid and sodium from the body. The combination of these two medications enhances the overall effectiveness in managing hypertension as they work through different mechanisms. This synergistic effect not only improves the control of blood pressure but also minimizes the risk of side effects associated with higher doses of a single medication.