Paroxetine is NOT recommended for use during which condition?

Paroxetine is classified as a selective serotonin reuptake inhibitor (SSRI) and is used to treat various conditions, including depression and anxiety disorders. However, it is not recommended for use during pregnancy due to its potential risks. Studies have indicated that paroxetine may be associated with an increased risk of congenital malformations, particularly cardiac defects, when used during the first trimester of pregnancy. This poses significant risks both to the developing fetus and to the health of the mother, making its use preferable to avoid during this critical period.

In contrast, while careful monitoring is necessary, paroxetine may be used in individuals with diabetes, insomnia, and hypertension, as there are no specific contraindications related to these conditions. In the case of diabetes, for example, paroxetine can sometimes assist in managing mood disorders that could exacerbate diabetes control. Similarly, though caution is needed with insomnia and hypertension to avoid exacerbating those conditions, paroxetine can still be utilized effectively with proper management. Therefore, it's the risks associated with paroxetine during pregnancy that make it inadvisable for use in that condition.