How should Nitroglycerin IV infusion be prepared?

The preparation of Nitroglycerin IV infusion is typically done in a D5W (5% dextrose in water) solution. This choice is correct because D5W is a compatible diluent that provides a suitable medium for the drug's stability and effectiveness. Nitroglycerin requires an appropriate environment to maintain its integrity and efficacy, and D5W is often used for this purpose.

Utilizing D5W helps in ensuring that the solution remains stable and reduces the risk of potential reactions that could occur with other types of solutions. This is particularly important since Nitroglycerin is sensitive to certain conditions, including the type of container or packaging used, which is why options involving plastic or metal are generally avoided for direct preparation.

The use of a plastic container could lead to leaching of chemicals, which may interfere with the medication. Metal syringes are not suitable for preparing Nitroglycerin due to the potential for chemical reactions with the drug. Lastly, a ceramic vial is not preferred as it does not provide the right conditions for storing or preparing solutions like Nitroglycerin IV infusions. Therefore, preparing Nitroglycerin in D5W solution aligns with best practices for ensuring drug safety and effectiveness.