How is the typhoid vaccine Vivotif administered?

The typhoid vaccine Vivotif is administered orally, which distinguishes it from many other vaccines that are given via injection. Vivotif is a live attenuated vaccine, meaning it contains a weakened form of the bacteria that causes typhoid fever. This oral administration allows the vaccine to stimulate an immune response in the gastrointestinal tract, where the bacteria would typically enter the body, leading to a more natural and effective immune response.

When patients take Vivotif, they typically do so in capsule form, which needs to be swallowed without chewing and with a sufficient amount of water. Because it is a live vaccine, the oral route facilitates the proper release of the attenuated bacteria within the digestive system, enhancing the body's ability to develop immunity against future infection.

Other forms of vaccine administration, such as intramuscular or subcutaneous injections, are common for many vaccines but not for Vivotif. This oral route is particularly beneficial for populations that may have trouble accessing or agreeing to injections, making it a practical choice in many scenarios.