How do you calculate absolute neutrophil count?

To calculate the absolute neutrophil count (ANC), the formula employed is based on the total white blood cell (WBC) count and the percentage of neutrophils and bands (immature neutrophils) in the blood. The correct choice accurately reflects this calculation: the WBC count should be multiplied by the combined percentage of neutrophils and bands, expressed as a fraction of 100.

In this context, obtaining the ANC involves summing the percentages of neutrophils and bands, indicating the total mature and immature neutrophil population that can respond to infection. The resulting number is then multiplied by the total WBC count to provide the absolute number of neutrophils in a defined volume of blood, which is critical in clinical settings for assessing a patient's immune status.

By distinguishing between neutrophils and bands, this calculation allows the medical professional to understand the body’s capacity to fight infections effectively, facilitating timely decisions regarding treatment options for patients.