For the treatment of Neisseria gonorrhoeae, what is the standard dosage of Ceftriaxone?

The standard dosage of Ceftriaxone for treating Neisseria gonorrhoeae is 500mg administered via intramuscular injection. This dosage is effective in achieving therapeutic levels to combat the infection while minimizing the potential for side effects commonly associated with higher doses.

In the context of treating gonorrhea, Ceftriaxone is commonly paired with azithromycin for enhanced efficacy and to address potential co-infection with Chlamydia trachomatis. This treatment regimen is designed to be both safe and effective, aligning with current clinical guidelines that recommend the specified dosage for uncomplicated gonorrhea.

Higher doses, such as 1g IM or 2g IV, may be used for other, more severe infections or different indications, but they are not recommended for this specific treatment. Thus, the 500mg IM dosage is established as the standard for effectively treating Neisseria gonorrhoeae.