Alteplase (tPA) is primarily used for which medical condition?

Alteplase (tPA), known as tissue plasminogen activator, is primarily recognized for its use in treating acute ischemic strokes. It works by dissolving blood clots that obstruct blood flow to the brain, thus minimizing the damage caused by the stroke. The timing of administration is critical, as tPA is most effective when given within a certain timeframe after the onset of symptoms.

While it can also be used to treat other conditions such as myocardial infarction (STEMI), pulmonary embolism, and deep vein thrombosis, its most significant and well-established role is in the management of stroke. The standard protocol and guidelines emphasize its application in this specific context, highlighting its preferential use for stroke treatment over other potential indications.