According to DSM-5 criteria, how many symptoms must a patient exhibit for a diagnosis of major depression?

In order to diagnose major depressive disorder according to the DSM-5 criteria, a patient must exhibit five or more specific symptoms during the same two-week period. These symptoms must represent a change from previous functioning and include either a depressed mood or a loss of interest or pleasure. The number of symptoms required aligns with the criteria’s emphasis on the severity and duration of the symptoms, which captures the intensity of the depressive episode.

This standard is set to ensure that the diagnosis is only applied when there is enough evidence of significant impairment in the individual's daily life, relationships, and overall functioning. The requirement of five or more symptoms distinguishes major depression from less severe mood disturbances, ensuring that a thorough assessment has been made of the patient's mental health status.